sábado, janeiro 22, 2005
CDC recomenda PEP não-ocupacional
CDC Recommends Prophylactic Antiretroviral Drug Regimen for People Exposed to HIV Through Unprotected Sex, Shared Needles
CDC on Thursday in a "major policy shift" recommended that people exposed to HIV through unprotected sexual intercourse, sexual assault, shared needles or accidents receive immediate treatment with antiretroviral drugs to prevent infection, the AP/Chicago Tribune reports (Yee, AP/Chicago Tribune, 1/21).
The move expands 1996 CDC guidelines that recommended post-exposure prophylaxis only for health care workers exposed to HIV through occupational accidents, USA Today reports (Manning, USA Today, 1/21). CDC said the new guidelines -- which were published on Friday in CDC's Morbidity and Mortality Weekly Report -- are based on studies showing that beginning an antiretroviral regimen shortly after exposure can reduce the risk of HIV infection by as much as 80% (Goldstein, Miami Herald, 1/21).
CDC said that to be effective, prophylactic antiretroviral regimens must be started no later than 72 hours after HIV exposure and continue for 28 days (McKay, Wall Street Journal, 1/21). CDC recommends that individuals take efavirenz and lamivudine or emtricitabine with zidovudine or tenofovir and lopinavir/ritonavir and zidovudine with either lamivudine or emtricitabine, but says that "[d]ifferent alternative regimens are possible" (Reuters, 1/20).
Some health professionals "applauded" CDC's new guidelines, the AP/ Sun reports. "We have probably the most conservative administration in the last 50 years, and yet the CDC is coming out with a policy that is more progressive than perhaps any country's in the world," Dr. Josh Bamberger of the San Francisco Department of Public Health, who helped create that city's policy on prophylactic HIV treatment, said, adding, "If you had unsafe sex while you were drunk or had a condom break, you should take these medicines -- that is what is recommended by the public health service of the United States. That's amazing" (Leff, AP/Las Vegas Sun, 1/21).